Su Guo

Su Guo is a faculty member at the University of California San Francisco with research spanning genetics, neuroscience, and developmental biology. Her work focuses on understanding how molecular and cellular mechanisms regulate neural development, cell fate decisions, and behavior, frequently using zebrafish as a powerful in vivo model system. A major theme of her research is asymmetric cell division and how centrosome dynamics, polarity proteins, and signaling pathways contribute to differential daughter cell outcomes during development. Her studies integrate cell biology, neurogenetics, and systems-level approaches to link molecular mechanisms with organism-level phenotypes, including neural function and behavior. She has contributed extensively to the literature on centrosome asymmetry, polarity regulation, and neurodevelopmental processes, with publications in high-impact journals such as Nature Communications and Science Advances. Through interdisciplinary collaborations, her research also explores how disruptions in developmental and cellular processes can inform understanding of neurological disorders and disease mechanisms.