Brian Aguado

Brian Aguado is an Assistant Professor of Bioengineering at the University of California San Diego, where he leads the Aguado iBiomaterials Research Group. His research focuses on developing precision biomaterials that enable the evaluation of patient-specific biology to better diagnose and treat disease as a function of sex, age, and ancestry. His lab integrates biomaterials engineering, tissue engineering, and immunoengineering to study how biological sex influences cardiovascular diseases such as aortic valve disease and heart failure. By operating across multiple length scales, the group investigates how sex hormones, sex chromosomes, cardiac cells, mechanical and biochemical cues from the tissue microenvironment, and inflammation contribute to sex-based differences in health and disease. This work aims to advance the development of more effective, sex-specific therapeutic strategies. Aguado earned his BS in Biomechanical Engineering from Stanford University and his MS and PhD in Biomedical Engineering from Northwestern University, along with a management certificate from the Kellogg School of Management. He completed postdoctoral training at the University of Colorado Boulder and has received support from NIH, NSF, and other major funding agencies.